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Cytokeratin 10 (Y160) polyclonal Antibody | BS1199
- SKU:
- BW-BS1199
- Availability:
- Usually ships in 5 working days
Description
Cytokeratin 10 (Y160) polyclonal Antibody | BS1199 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: IHC IF
Application Range: IHC: 1:50~1:200 IF: 1:50~1:200
Background: Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 10 is a heterotetramer of two type I and two type II keratins, is generally associated with keratin 1, and is seen in all suprabasal cell layers including stratum corneum.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Cytokeratin 10 (Y160) polyclonal Antibody detects endogenous levels of Cytokeratin 10 protein.
Molecular Weight: ~ 59 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Keratin, type I cytoskeletal 10; Cytokeratin-10; Short name=CK-10; Keratin-10; Short name=K10; KRT10; KPP; CK-10; CK 10; CK10; Keratin 10; Keratin10
Immunogen: Synthetic peptide, corresponding to amino acids 130-180 of Human Cytokeratin 10.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: