(DANRE) rho Antibody (N-Term) [APR33110G]

(DANRE) rho Antibody (N-Term) [APR33110G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: Zf

Specificity: This DANRE rho antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 62-93 amino acids from the human region of DANRE rho.

Cellular Localisation: Membrane {ECO:0000250|UniProtKB:P08100}; Multi- pass membrane protein {ECO:0000250|UniProtKB:P08100}. Cell projection, cilium, photoreceptor outer segment Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia. {ECO:0000250|UniProtKB:P08100}

Molecular Weight: 39706

Clone: Polyclonal

Gene Name: rho

Gene ID: 30295

Function: Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity) . Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity) .

Summary: Tissue Location: Retinal rod photoreceptor cells, predominantly in the outer segments (at protein level) (PubMed:10349976) . Retinal rod photoreceptor cells (PubMed:8327475, PubMed:8603882)

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Rhodopsin, rho, zfo2