(DANRE) srrt Antibody (C-Term) [APR33255G]

(DANRE) srrt Antibody (C-Term) [APR33255G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This DANRE srrt antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 878-910 amino acids from DANRE srrt.

Cellular Localisation: Nucleus, nucleoplasm. Cytoplasm. Note=Predominantly nuclear. Shuttles between the nucleus and the cytoplasm (By similarity) .

Molecular Weight: 103274

Clone: Polyclonal

Gene Name: srrt

Gene ID: 192311

Function: Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity) . Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity) .

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Serrate RNA effector molecule homolog, Arsenite-resistance protein 2, srrt, ars2