DCXR, human recombinant | P1155

Dicarbonyl/L-xylulose reductase, also known as DCXR, is an enzyme responsible for the metabolism of xylulose, converting it into xylitol. DCXR was expressed at low levels and was localized predominantly in the cytoplasmic membrane. In contrast, in virtually all grades of early-stage prostate cancer and in all chemohormonally treated cases, DCXR was strikingly overexpressed and was localized predominantly in the cytoplasm and nucleus. Recombinant human DCXR, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

P1155 | DCXR human recombinant DataSheet

Biomolecule/Target: DCXR

Synonyms: Dicarbonyl/L-xylulose reductase, DCR, HCR2, HCRII, KIDCR, P34H

Alternates names: apm-1, Adipolean , 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, Adipocyte, C1q and collagen domain-containing protein, Adipose most abundant gene transcript 1 protein, Gelatin-binding protein, ADIPOQ, ACDC, ACRP30, APM1, GBP28

Taglines: Converts xylulose into xylitol

NCBI Gene ID #: 11450

NCBI Gene Symbol: ADIPOQ

Gene Source: Human

Accession #: Q60994

Recombinant: Yes

Source: E.coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): Measured by its ability to oxidize 1 pmole of xylitol to L-xylulose per minute at pH 10 at 37C

Biological activity: Determined by its ability to inhibit the proliferation of murine myeloid cell lines M1. The ED for this effect is less than 15 µg/ml.

Results: > 1,800 pmol/min/ug

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 16.6 kDa

Concentration: N/A

Appearance: Liquid

Physical form description: In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 20% glycerol, 50 mM NaCl

Reconstitution Instructions: Reconstitute in 5 mM Tris, pH 7.6 to a concentration of 0.1-1.0 mg/ml. This stock solution can then be diluted into other aqueous buffers

Amino acid sequence: N/A