26
DCXR, human recombinant | P1155
- SKU:
- 26-P1155-GEN
- Availability:
- Usually shipped in 5 working days
Description
Dicarbonyl/L-xylulose reductase, also known as DCXR, is an enzyme responsible for the metabolism of xylulose, converting it into xylitol. DCXR was expressed at low levels and was localized predominantly in the cytoplasmic membrane. In contrast, in virtually all grades of early-stage prostate cancer and in all chemohormonally treated cases, DCXR was strikingly overexpressed and was localized predominantly in the cytoplasm and nucleus. Recombinant human DCXR, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
P1155 | DCXR human recombinant DataSheet
Biomolecule/Target: DCXR
Synonyms: Dicarbonyl/L-xylulose reductase, DCR, HCR2, HCRII, KIDCR, P34H
Alternates names: apm-1, Adipolean , 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, Adipocyte, C1q and collagen domain-containing protein, Adipose most abundant gene transcript 1 protein, Gelatin-binding protein, ADIPOQ, ACDC, ACRP30, APM1, GBP28
Taglines: Converts xylulose into xylitol
NCBI Gene ID #: 11450
NCBI Gene Symbol: ADIPOQ
Gene Source: Human
Accession #: Q60994
Recombinant: Yes
Source: E.coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): Measured by its ability to oxidize 1 pmole of xylitol to L-xylulose per minute at pH 10 at 37C
Biological activity: Determined by its ability to inhibit the proliferation of murine myeloid cell lines M1. The ED for this effect is less than 15 µg/ml.
Results: > 1,800 pmol/min/ug
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 16.6 kDa
Concentration: N/A
Appearance: Liquid
Physical form description: In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 20% glycerol, 50 mM NaCl
Reconstitution Instructions: Reconstitute in 5 mM Tris, pH 7.6 to a concentration of 0.1-1.0 mg/ml. This stock solution can then be diluted into other aqueous buffers
Amino acid sequence: N/A