Description
A small-molecule inhibitor of the mammalian target of rapamycin (mTOR). Blocking mTOR creates a starvation-like effect in cancer cells by interfering with cell growth, division, metabolism, and angiogenesis.
Deforolimus is a small-molecule inhibitor of the mammalian target of rapamycin (mTOR).
Alternate Name/Synonyms: AP 23573, MK-8669, Ridaforolimus
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 572924-54-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₅₃H₈₄NO₁₄P
Molecular Weight: 989.56
Cell-Permeable?: Yes
Purity: ≥99% by HPLC
Solubilities: DMSO
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A mTOR inhibitor
MDL Number: MFCD13184816
PubChem CID: 23724531
SMILES: CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OP(=O)(C)C)C)C)O)OC)C)C)C)OC
InChi: InChI=1S/C53H84NO14P/c1-32-18-14-13-15-19-33(2)44(63-8)30-40-23-21-38(7)53(61,67-40)50(58)51(59)54-25-17-16-20-41(54)52(60)66-45(35(4)28-39-22-24-43(46(29-39)64-9)68-69(11,12)62)31-42(55)34(3)27-37(6)48(57)49(65-10)47(56)36(5)26-32/h13-15,18-19,27,32,34-36,38-41,43-46,48-49,57,61H,16-17,20-26,28-31H2,1-12H3/b15-13+,18-14+,33-19+,37-27+/t32-,34-,35-,36-,38-,39+,40?,41+, 43-,44+,45+,46-,48-,49+,53-/m1/s1
InChi Key: BUROJSBIWGDYCN-KMXFESHVSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24months |