(-)-Deguelin | B2096

Deguelin is a naturally occurring flavonoid that displays potent antiproliferative, antimetastatic, and apoptotic activity against several cancers both in vitro and in vivo. deguelin induces cell death by inhibiting several cell signaling pathways, such as PI3K-Akt, IKK-IκBα-NF-κB, AMPK-mTOR-survivin, and HIF-1α-VEGF.

Deguelin is a naturally occurring flavonoid that displays potent antiproliferative, antimetastatic, and apoptotic activity against several cancers both in vitro and in vivo. deguelin induces cell death by inhibiting several cell signaling pathways, such as PI3K-Akt, IKK-IκBα-NF-κB, AMPK-mTOR-survivin, and HIF-1α-VEGF.

B2096 | (-)-Deguelin DataSheet

Alternate Name/Synonyms: (7aS,13aS)-13,13a-Dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6′,5′-e]pyran-7(7aH)-one

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 522-17-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₂₂O₆

Molecular Weight: 394.42

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A naturally occurring flavonoid that displays various biological activities

MDL Number: MFCD01740600

PubChem CID: 107935

SMILES: CC1(C=CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC)C

InChi: InChI=1S/C23H22O6/c1-23(2)8-7-12-15(29-23)6-5-13-21(24)20-14-9-17(25-3)18(26-4)10-16(14)27-11-19(20)28-22(12)13/h5-10,19-20H,11H2,1-4H3/t19-,20+/m1/s1

InChi Key: ORDAZKGHSNRHTD-UXHICEINSA-N