Description
Delafloxacin (ABT-492) is a fluoroquinolone antibiotic that displays high potency against a wide range of bacteria in vitro, including levofloxacin-resistant strains of S. pneumoniae and methicillin-resistant S. aureus. It targets both DNA gyrase and topoisomerase IV.
Delafloxacin (ABT-492) is a fluoroquinolone antibiotic that displays high potency against a wide range of bacteria in vitro, including levofloxacin-resistant strains of S. pneumoniae and methicillin-resistant S. aureus. It targets both DNA gyrase and topoisomerase IV.
B1950 | Delafloxacin DataSheet
Alternate Name/Synonyms: 1-(6-Amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; ABT-492; RX-3341
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 189279-58-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₈H₁₂ClF₃N₄O₄
Molecular Weight: 440.76
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~0.5 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A fluoroquinone antibiotic that displays high potency against a wide range of bacteria
MDL Number: MFCD09955301
PubChem CID: 487101
SMILES: C1C(CN1C2=C(C=C3C(=C2Cl)N(C=C(C3=O)C(=O)O)C4=NC(=C(C=C4F)F)N)F)O
InChi: InChI=1S/C18H12ClF3N4O4/c19-12-13-7(1-9(20)14(12)25-3-6(27)4-25)15(28)8(18(29)30)5-26(13)17-11(22)2-10(21)16(23)24-17/h1-2,5-6,27H,3-4H2,(H2,23,24)(H,29,30)
InChi Key: DYDCPNMLZGFQTM-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |