LBD
DEN1A Antibody (C-term) [APR11729G]
- SKU:
- LBD-APR11729G
- Availability:
- Usually ships in 5 working days
Description
DEN1A Antibody (C-term) [APR11729G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This DEN1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 576-605 amino acids from the C-terminal region of human DEN1A.
Cellular Localisation: Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein. Cell junction, synapse, presynaptic cell membrane. Note=Associates to membranes via lipid- binding activity. {ECO:0000250|UniProtKB:Q8K382}
Molecular Weight: 110577
Clone: Polyclonal
Gene Name: DENND1A (HGNC:29324)
Gene ID: 57706
Function: Guanine nucleotide exchange factor (GEF) regulating clathrin- mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP- bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes (PubMed:20154091, PubMed:20937701) . Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns (3) P (By similarity) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: IHC-P, FC, WB
Dilution: WB--1:500 IHC-P--1:100~500 FC--1:10~50
Synonyms: DENN domain-containing protein 1A, Connecdenn 1, Connecdenn, Protein FAM31A, DENND1A, FAM31A, KIAA1608