Description
A fungal metabolite that acts as a potent HDAC inhibitor (IC50 = 4.7 µM for HDAC1). It reverts ras- and src-transformed NIH3T3 cells to a flat phenotype (1 µg/ml).
Depudecin is a fungal metabolite that acts as a potent HDAC inhibitor (IC50 = 4.7 µM for HDAC1). It reverts ras- and src-transformed NIH3T3 cells to a flat phenotype (1 µg/ml).
Alternate Name/Synonyms: 4,5:8,9-Dianhydro-1,2,6,7,11-pentadeoxy-D-threo-D-ido-undeca-1,6-dienitol
Appearance: Liquid
Formulation: N/A
CAS Number: 139508-73-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₁₁H₁₆O₄
Molecular Weight: 212.24
Cell-Permeable?: Yes
Purity: ≥95% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A HDAC inhibitor
MDL Number: MFCD04039998
PubChem CID: 16219259
SMILES: CC(C1C(O1)C=CC2C(O2)C(C=C)O)O
InChi: InChI=1S/C11H16O4/c1-3-7(13)11-9(15-11)5-4-8-10(14-8)6(2)12/h3-13H,1H2, 2H3/b5-4+/t6-,7-,8+,9+,10+,11+/m1/s1
InChi Key: DLVJMFOLJOOWFS-INMLLLKOSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Dry ice |
Shelf Life: |
12 months |