Destruxin A | B2947

Destruxin A is a cyclic hexadepsipeptide metabolite from the fungus Metarhizium anisopliae. Destruxins show insecticidal, anti-viral, and phytotoxic properties. Destruxin A suppresses the Drosophila humoral immune response in Drosophila melanogaster. It increases peptidoglycan recognition protein (PGRP), prophenoloxidase (proPO) system and affects diverse pathways, including apoptosis, calcium signaling, and development in the larvae of Plutella xylostella.

Destruxin A is a cyclic hexadepsipeptide metabolite from the fungus Metarhizium anisopliae. Destruxins show insecticidal, anti-viral, and phytotoxic properties. Destruxin A suppresses the Drosophila humoral immune response in Drosophila melanogaster. It increases peptidoglycan recognition protein (PGRP), prophenoloxidase (proPO) system and affects diverse pathways, including apoptosis, calcium signaling, and development in the larvae of Plutella xylostella.

B2947 | Destruxin A DataSheet

Alternate Name/Synonyms: 3-(butan-2-yl)-5,8,9-trimethyl-6-(propan-2-yl)-16-(prop-2-en-1-yl)dodecahydropyrrolo[1,2-d][1,4,7,10,13,16]oxapentaazacyclononadecine-1,4,7,10,14,17(11h,16h)-hexone; (3S,6S,9S,16R,21aS)-16-Allyl-3-[(2S)-2-butanyl]-6-isopropyl-5,8,9-trimethyldodecahydropyrrolo[1,2-d][1,4,7,10,13,16]oxapentaazacyclononadecine-1,4,7,10,14,17(11H,16H)-hexone; NSC361126

Appearance: Solid

Formulation:

CAS Number: 6686-70-0

Structure Available?: True

Peptide sequence:

Salt Form: false

Molecular Formula: C₂₉H₄₇N₅O₇

Molecular Weight: 577.71

Cell-Permeable?: True

Purity: ≥96%

Solubilities: 10 mg/ml in in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A cyclic hexa-depsipeptide with insecticidal, anti-viral, and phytotoxic properties

MDL Number:

PubChem CID: 122810

SMILES: CCC(C)C1C(=O)N(C(C(=O)N(C(C(=O)NCCC(=O)OC(C(=O)N2CCCC2C(=O)N1)CC=C)C)C)C(C)C)C

InChi: InChI=1S/C29H47N5O7/c1-9-12-21-27(38)34-16-11-13-20(34)26(37)31-23(18(5)10-2)28(39)33(8)24(17(3)4)29(40)32(7)19(6)25(36)30-15-14-22(35)41-21/h9,17-21,23-24H,1,10-16H2,2-8H3,(H,30,36)(H,31,37)

InChi Key: XIYSEKITPHTMJT-UHFFFAOYSA-N