Description
Destruxin A is a cyclic hexadepsipeptide metabolite from the fungus Metarhizium anisopliae. Destruxins show insecticidal, anti-viral, and phytotoxic properties. Destruxin A suppresses the Drosophila humoral immune response in Drosophila melanogaster. It increases peptidoglycan recognition protein (PGRP), prophenoloxidase (proPO) system and affects diverse pathways, including apoptosis, calcium signaling, and development in the larvae of Plutella xylostella.
Destruxin A is a cyclic hexadepsipeptide metabolite from the fungus Metarhizium anisopliae. Destruxins show insecticidal, anti-viral, and phytotoxic properties. Destruxin A suppresses the Drosophila humoral immune response in Drosophila melanogaster. It increases peptidoglycan recognition protein (PGRP), prophenoloxidase (proPO) system and affects diverse pathways, including apoptosis, calcium signaling, and development in the larvae of Plutella xylostella.
Alternate Name/Synonyms: 3-(butan-2-yl)-5,8,9-trimethyl-6-(propan-2-yl)-16-(prop-2-en-1-yl)dodecahydropyrrolo[1,2-d][1,4,7,10,13,16]oxapentaazacyclononadecine-1,4,7,10,14,17(11h,16h)-hexone; (3S,6S,9S,16R,21aS)-16-Allyl-3-[(2S)-2-butanyl]-6-isopropyl-5,8,9-trimethyldodecahydropyrrolo[1,2-d][1,4,7,10,13,16]oxapentaazacyclononadecine-1,4,7,10,14,17(11H,16H)-hexone; NSC361126
Appearance: Solid
Formulation:
CAS Number: 6686-70-0
Structure Available?: True
Peptide sequence:
Salt Form: false
Molecular Formula: C₂₉H₄₇N₅O₇
Molecular Weight: 577.71
Cell-Permeable?: True
Purity: ≥96%
Solubilities: 10 mg/ml in in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A cyclic hexa-depsipeptide with insecticidal, anti-viral, and phytotoxic properties
MDL Number:
PubChem CID: 122810
SMILES: CCC(C)C1C(=O)N(C(C(=O)N(C(C(=O)NCCC(=O)OC(C(=O)N2CCCC2C(=O)N1)CC=C)C)C)C(C)C)C
InChi: InChI=1S/C29H47N5O7/c1-9-12-21-27(38)34-16-11-13-20(34)26(37)31-23(18(5)10-2)28(39)33(8)24(17(3)4)29(40)32(7)19(6)25(36)30-15-14-22(35)41-21/h9,17-21,23-24H,1,10-16H2,2-8H3,(H,30,36)(H,31,37)
InChi Key: XIYSEKITPHTMJT-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36months |