Dexamethasone phosphate disodium | B2744

Dexamethasone phosphate is a water-soluble form of the synthetic glucocorticoid anti-inflammatory agent dexamethasone (Cat. No. 1042). Recently, it has been shown that in patients hospitalized with COVID-19, dexamethasone reduces 28-day mortality among those receiving invasive mechanical ventilation or oxygen at randomization, but not among patients not receiving respiratory support.

Dexamethasone phosphate is a water-soluble form of the synthetic glucocorticoid anti-inflammatory agent dexamethasone (Cat. No. 1042). Recently, it has been shown that in patients hospitalized with COVID-19, dexamethasone reduces 28-day mortality among those receiving invasive mechanical ventilation or oxygen at randomization, but not among patients not receiving respiratory support.

B2744 | Dexamethasone phosphate disodium DataSheet

Alternate Name/Synonyms: (11β,16α)-9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-pregna-1,4-diene-3,20-dione, disodium salt

Appearance: White to off-white solid

Formulation:

CAS Number: 2392-39-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₈FO₈P • 2Na

Molecular Weight: 516.4

Cell-Permeable?: FALSE

Purity: ≥98% by HPLC

Solubilities: >100 mg/ml Water

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An anti-inflammatory glucocorticoid

MDL Number: MFCD00079105

PubChem CID: 16961

SMILES: O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2(F)[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@@H](C)[C@]4(O)C(COP([O-])([O-])=O)=O)=C1.[Na+].[Na+]

InChi: InChI=1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15+,16+,17+,19+,20+,21+,22+;;/m1../s1

InChi Key: PLCQGRYPOISRTQ-FCJDYXGNSA-L