LBD
DGKD Antibody (C-term) [APR15729G]
- SKU:
- LBD-APR15729G
- Availability:
- Usually ships in 5 working days
Description
DGKD Antibody (C-term) [APR15729G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This DGKD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1061-1091 amino acids from the C-terminal region of human DGKD.
Cellular Localisation: Membrane, clathrin-coated pit. Cytoplasm
Molecular Weight: 134525
Clone: Polyclonal
Gene Name: DGKD (HGNC:2851)
Gene ID: 8527
Function: Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:12200442, PubMed:23949095) . Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable) . By controlling the levels of diacylglycerol, regulates for instance the PKC and EGF receptor signaling pathways and plays a crucial role during development (By similarity) . May also regulate clathrin-dependent endocytosis (PubMed:17880279) .
Summary: Tissue Location: [Isoform 2]: Widely expressed.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P
Dilution: WB--1:1000 IHC-P--1:100~500
Synonyms: Diacylglycerol kinase delta, DAG kinase delta, 130 kDa diacylglycerol kinase, Diglyceride kinase delta, DGK-delta, DGKD, KIAA0145