LBD
DHRS11 Antibody (Center) [APR31604G]
- SKU:
- LBD-APR31604G
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Description
DHRS11 Antibody (Center) [APR31604G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This DHRS11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-142 amino acids from the Central region of human DHRS11.
Cellular Localisation: Secreted.
Molecular Weight: 28308
Clone: Polyclonal
Gene Name: DHRS11
Gene ID: 79154
Function: Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta- hydroxyl metabolites and the conversion of the 3-keto group of 3-, 3, 17- and 3, 20- diketosteroids into their 3-hydroxyl metabolites. Exhibits reductive 3-beta-hydroxysteroid dehydrogenase activity toward 5-beta-androstanes, 5-beta-pregnanes, 4-pregnenes and bile acids. May also reduce endogenous and exogenous alpha-dicarbonyl compounds and xenobiotic alicyclic ketones.
Summary: Tissue Location: Isoform 1: Ubiquitously expressed, with highest levels in testis, small intestine, colon, kidney, brain and heart Isoform 3: Expressed in brain, heart and skeletal muscle
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Dehydrogenase/reductase SDR family member 11, 1---, DHRS11