Description
Dibromobimane, a bifunctional thiol-reactive fluorescent reagent that is used as a cross-linking agent for cysteine mapping and studies on protein structure/conformation and cross-linking processes. It is a unique fluorogenic crosslinking reagent for proteins due to the fact that it is unlikely to fluoresce until both of its alkylating groups have reacted. The excitation and emission maxima for dibromobimane are 394 and 490 nm, respectively.
Dibromobimane, a bifunctional thiol-reactive fluorescent reagent that is used as a cross-linking agent for cysteine mapping and studies on protein structure/conformation and cross-linking processes. It is a unique fluorogenic crosslinking reagent for proteins due to the fact that it is unlikely to fluoresce until both of its alkylating groups have reacted. The excitation and emission maxima for dibromobimane are 394 and 490 nm, respectively.
B2673 | Dibromobimane DataSheet
Alternate Name/Synonyms: NSC608550,syn-(bromomethyl,methyl)bimane,1,7-bis(bromomethyl)-2,6-dimethylpyrazolo[1,2-a]pyrazole-3,5-dione,NSC-608550,Thiolyte BB,dBBr
Appearance: Crystalline solid
Formulation:
CAS Number: 68654-25-1
Structure Available?: Yes
Peptide sequence:
Salt Form: No
Molecular Formula: C₁₀H₁₀Br₂N₂O₂
Molecular Weight: 350.01
Cell-Permeable?: True
Purity: ≥95%
Solubilities: DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A thiol-reactive fluorescent probe
MDL Number: MFCD00036952
PubChem CID: 125708
SMILES: CC1=C(N2C(=C(C(=O)N2C1=O)C)CBr)CBr
InChi: InChI=1S/C10H10Br2N2O2/c1-5-7(3-11)13-8(4-12)6(2)10(16)14(13)9(5)15/h3-4H2,1-2H3
InChi Key: OSIYFMVMZXJKSP-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |