Description
Dichlorphenamide is a potent, orally bioavailable carbonic anhydrase (CA) inhibitor (Kis = 1.20, 38, 50, and 50 nM for the human CA isoforms CAI, CAII, CAIX, and CAXII, respectively). It lowers intraocular pressure in rabbits when 50 µl of a 10% solution is applied topically to the eye. Used in the treatment of glaucoma and primary periodic paralysis.
Dichlorphenamide is a potent, orally bioavailable carbonic anhydrase (CA) inhibitor (Kis = 1.20, 38, 50, and 50 nM for the human CA isoforms CAI, CAII, CAIX, and CAXII, respectively). It lowers intraocular pressure in rabbits when 50 µl of a 10% solution is applied topically to the eye. Used in the treatment of glaucoma and primary periodic paralysis.
B3272 | Dichlorphenamide DataSheet
Alternate Name/Synonyms: Diclofenamide 4,5-dichloro-1,3-benzenedisulfonamide
Appearance: Solid
Formulation:
CAS Number: 120-97-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₆H₆Cl₂N₂O₄S₂
Molecular Weight: 305.16
Cell-Permeable?: True
Purity: ≥98%
Solubilities:
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent carbonic anhydrase inhibitor
MDL Number: MFCD00148948
PubChem CID: 3038
SMILES: C1=C(C=C(C(=C1S(=O)(=O)N)Cl)Cl)S(=O)(=O)N
InChi: InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14)
InChi Key: GJQPMPFPNINLKP-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |