Digoxin | 2911

Digoxin is a cardiac glycoside from the leaves of Digitalis lanata. It is used to treat cardiac arrhythmias. It is often used as a model substrate of P-glycoprotein (0.01-10 µM) and an inhibitor of Na+/K+-ATPase.

Digoxin is a cadiac glycoside used to treat arrhythmias. It is a potent substrate for P-glycoprotein or MDR1.

2911 | Digoxin DataSheet

Alternate Name/Synonyms: 12 beta-Hydroxydigitoxin, Lanoxin

Appearance: Clear to white crystalline powder

Formulation: N/A

CAS Number: 20830-75-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₄₁H₆₄O₁₄

Molecular Weight: 780.95

Cell-Permeable?: N/A

Purity: ≥96% by HPLC

Solubilities: Pyridine (50 mg/ml), DMSO (>70 mg/ml)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A P-glycoprotein model substrate

MDL Number: MFCD00003674

PubChem CID: 87568294

SMILES: CC1C(C(CC(O1)OC2C(OC(CC2O)OC3C(OC(CC3O)OC4CCC5(C(C4)CCC6C5CC(C7(C6(CCC7C8=CC(=O)OC8)O)C)O)C)C)C)O)O

InChi: InChI=1S/C41H64O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,19-21,23-31,33-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1

InChi Key: LTMHDMANZUZIPE-PUGKRICDSA-N