Description
Digoxin is a cardiac glycoside from the leaves of Digitalis lanata. It is used to treat cardiac arrhythmias. It is often used as a model substrate of P-glycoprotein (0.01-10 µM) and an inhibitor of Na+/K+-ATPase.
Digoxin is a cadiac glycoside used to treat arrhythmias. It is a potent substrate for P-glycoprotein or MDR1.
Alternate Name/Synonyms: 12 beta-Hydroxydigitoxin, Lanoxin
Appearance: Clear to white crystalline powder
Formulation: N/A
CAS Number: 20830-75-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₄₁H₆₄O₁₄
Molecular Weight: 780.95
Cell-Permeable?: N/A
Purity: ≥96% by HPLC
Solubilities: Pyridine (50 mg/ml), DMSO (>70 mg/ml)
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A P-glycoprotein model substrate
MDL Number: MFCD00003674
PubChem CID: 87568294
SMILES: CC1C(C(CC(O1)OC2C(OC(CC2O)OC3C(OC(CC3O)OC4CCC5(C(C4)CCC6C5CC(C7(C6(CCC7C8=CC(=O)OC8)O)C)O)C)C)C)O)O
InChi: InChI=1S/C41H64O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,19-21,23-31,33-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1
InChi Key: LTMHDMANZUZIPE-PUGKRICDSA-N
Additional Information
Storage Condition: |
RT |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |