Diphenyleneiodonium chloride | 2358

An irreversible inhibitor of iNOS and eNOS with IC50 values of 50 nM and 0.3 µM, respectively. Also inhibits other flavoenzymes such as neutrophil NADPH oxidase.

Diphenyleneiodonium chloride is a irreversible inhibitor of iNOS and eNOS with IC₅₀ values of 50 nM and 0.3 µM, respectively.

2358 | Diphenyleneiodonium chloride DataSheet

Alternate Name/Synonyms: Dibenziodolium chloride; DPI Chloride

Appearance: White solid

Formulation: N/A

CAS Number: 4673-26-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₂H₈I · Cl

Molecular Weight: 314.55

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: DMSO (warming, 5 mg/ml) or EtOH (0.2 mg/ml)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: An irreversible inhibitor of iNOS and eNOS

MDL Number: MFCD00214165

PubChem CID: 2733504

SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3[I+]2.[Cl-]

InChi: InChI=1S/C12H8I.ClH/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11;/h1-8H;1H/q+

InChi Key: FCFZKAVCDNTYID-UHFFFAOYSA-M