Dithranol | B3203

Dithranol is a leukotriene biosynthesis inhibitor. It inhibits LTB4 ω-oxidation and disrupts mitochondria function. Dithranol is highly effective in the treatment of psoriasis. The drug inhibits keratinocyte hyperproliferation, granulocyte function and, in addition, may exert an immunosuppressive effect.

Dithranol is a leukotriene biosynthesis inhibitor. It inhibits LTB4 ω-oxidation and disrupts mitochondria function. Dithranol is highly effective in the treatment of psoriasis. The drug inhibits keratinocyte hyperproliferation, granulocyte function and, in addition, may exert an immunosuppressive effect.

B3203 | Dithranol DataSheet

Alternate Name/Synonyms: 1,8,9-Anthracenetriol,1,8-Dihydroxy-9(10H)-anthracenone,Anthralin

Appearance: Light yellow to brown solid

Formulation:

CAS Number: 1143-38-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₄H₁₀O₃

Molecular Weight: 226.23

Cell-Permeable?: TRUE

Purity: ≥95% by HPLC

Solubilities: >10 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A leukotriene biosynthesis inhibitor

MDL Number: MFCD00053409

PubChem CID: 2202

SMILES: C1C2=C(C(=CC=C2)O)C(=O)C3=C1C=CC=C3O

InChi: InChI=1S/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2

InChi Key: NUZWLKWWNNJHPT-UHFFFAOYSA-N