Description
DLG7 Antibody | XW-7677 | Gentaur UK, US & Europe Distribution
Host: Chicken
Reactivity: Human
Homology: N/A
Immunogen: 1-300
Research Area: Other
Tested Application: WB
Application: DLG7 antibody can be used for the detection of Discs large homolog 7 by Western Blot.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 95.1 kDa (calculated)
Validation: N/A
Isoform: N/A
Purification: Immunoaffinity Purified
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Condition: DLG7 antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: DLG7, KIAA0008, Disks large-associated protein 5, Discs large homolog 7, DAP-5, DLG7, HURP, Hepatoma up-regulated protein
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: FUNCTION: Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
SUBUNIT: Interacts with CDC2. Interacts with the C-terminal proline-rich region of FBXO7. Recruited by FBXO7 to a SCF (SKP1-CUL1-F-box) protein complex in a CDC2/Cyclin B-phosphorylation dependent manner. Interacts with CDH1.