LBD
DLL4 Antibody (C-term) [APR11755G]
- SKU:
- LBD-APR11755G
- Availability:
- Usually ships in 5 working days
Description
DLL4 Antibody (C-term) [APR11755G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This DLL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 625-652 amino acids from the C-terminal region of human DLL4.
Cellular Localisation: Cell membrane; Single-pass type I membrane protein
Molecular Weight: 74605
Clone: Polyclonal
Gene Name: DLL4
Gene ID: 54567
Function: Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954) . Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313) . Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity) . During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344) .
Summary: Tissue Location: Expressed in vascular endothelium.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P, FC
Dilution: WB--1:1000
Synonyms: Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4