DNAJA4 Antibody | 8141

DNAJA4 Antibody | 8141 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Bovine: (87%)

Immunogen: DNAJA4 antibody was raised against a 15 amino acid peptide near the center of human DNAJA4.
The immunogen is located within amino acids 210 - 260 of DNAJA4.

Research Area: Homeostasis

Tested Application: E, WB

Application: DNAJA4 antibody can be used for detection of DNAJA4 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Specificiy: DNAJA4 antibody is human, mouse, and rat reactive. At least three isoforms of DNAJA4 are known to exist; this antibody will detect all three isoforms.

Positive Control 1: Cat. No. 1320 - Human Colon Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 41, 44, 47 kDa
Observed: 40 kDa

Validation: N/A

Isoform: N/A

Purification: DNAJA4 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: DNAJA4 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: DNAJA4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: DnaJ homolog subfamily A member 4, MST104, MSTP104, PRO1472

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The DNAJA4 protein is the mammalian homolog of the chaperone HSP40 (1) and acts as a co-chaperone with the heat shock protein HSP70 (2) . DNAJA4 is highly expressed in heart and testis, accounting for approximately 1% of total protein in mouse heart (2) . DNAJA4 is also regulated by the sterol regulatory element binding transcription factor 2 (SREBF2) and plays a role in the synthesis of cholesterol (3) .