Description
DRAGON Antibody | 57-567 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: This DRAGON (RGMB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-406 amino acids from the C-terminal region of human DRAGON (RGMB) .
Research Area: Neuroscience, Signal Transduction
Tested Application: WB, IHC-P
Application: For WB starting dilution is: 1:2000
For IHC-P starting dilution is: 1:10~50
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 48 kDa
Validation: N/A
Isoform: N/A
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Clonality: Polyclonal
Clone: N/A
Isotype: Rabbit Ig
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: batch dependent
Storage Condition: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: RGM domain family member B, DRG11-responsive axonal guidance and outgrowth of neurite, DRAGON, RGMB
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Repulsive Guidance Molecule B (RGMB) is primarily expressed in the central nervous system. RGM A and B both appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGMA appears in the neuroepithelium, and only RGMB in the peripheral nervous system. During development, both RGMA and B appear also in lung and in limb cartilage, while RGMB has additional expression domains in pancreas.