DRAGON (RGMB) Antibody (C-term) [APR11798G]

DRAGON (RGMB) Antibody (C-term) [APR11798G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This DRAGON (RGMB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-406 amino acids from the C-terminal region of human DRAGON (RGMB) .

Cellular Localisation: Cell membrane {ECO:0000250|UniProtKB:Q7TQ33}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q7TQ33}. Membrane raft {ECO:0000250|UniProtKB:Q7TQ33}

Molecular Weight: 47547

Clone: Polyclonal

Gene Name: RGMB {ECO:0000303|PubMed:19324014, ECO:0000312|HGNC:HGNC:26896}

Gene ID: 285704

Function: Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity) . Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity) . Promotes neuronal adhesion (By similarity) . May inhibit neurite outgrowth.

Summary: N/A

Form: Purified rabbit polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, WB

Dilution: IHC-P--1:100~500 WB--1:1000

Synonyms: RGM domain family member B, DRG11-responsive axonal guidance and outgrowth of neurite, DRAGON, RGMB