Drebrin Polyclonal Antibody | BS65925

Drebrin Polyclonal Antibody | BS65925 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,

Application: IHC-P,

Application Range: IHC-P=1:100-500

Background: Drebrin is a major neuronal F-actin binding protein involved in the control of actin dynamics and neuronal morphogenesis. Three major isoforms of drebrin, resulting from alternative splicing of a single gene, have been identified in the brain: the embryonic isoforms designated E1 and E2 and the adult or A isoform (95-120 kDa) . An additional truncated form of drebrin A, s-drebrin/A2 (42 kDa), is specifically expressed in the adult brain, but not in non-neuronal tissues. Drebrin is also widely expressed in a variety of cells including epithelial, endothelial, and smooth muscle cells and is associated at cell-cell adhering junction sites.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Drebrin Polyclonal Antibody detects endogenous levels of Drebrin protein.

Molecular Weight: 71kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: D0S117E; DBN 1; DBN1; Developmentally regulated brain protein; Developmentally-regulated brain protein; DKFZp434D064; DREB_HUMAN; Drebrin 1; Drebrin; Drebrin E; Drebrin1; DrebrinE.

Immunogen: KLH conjugated synthetic peptide derived from human Drebrin:151-250/651

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: