Description
DTNBP1 polyclonal Antibody | BS6806 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC IF
Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100
Background: Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: DTNBP1 polyclonal Antibody detects endogenous levels of DTNBP1 protein.
Molecular Weight: ~ 48 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: DTBP1; DTNBP1; Dysbindin; Dysbindin-1; Dystrobrevin binding protein 1; Dystrobrevin-binding protein 1; Hermansky Pudlak syndrome 7 protein; Hermansky-Pudlak syndrome 7 protein; HPS7; HPS7 protein;
Immunogen: Recombinant full length Human DTNBP1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: