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DUB Inhibitor, NSC-632839 | 2570
- SKU:
- 26-2570-GEN
- Availability:
- Usually shipped in 5 working days
Description
Cell-permeable. A pan-specific ubiquitin isopeptidase inhibitor (IC₅₀ = 45, 37 and 9.8 µM for USP2, USP7 and SENP2 respectively). NSC-632839 does not affect proteasome proteolytic activity. Induces apoptosis via a Bcl-2-dependent but apoptosome-independent mitochondrial pathway.
NSC-632839 is a pan-specific ubiquitin isopeptidase inhibitor (IC₅₀ = 45, 37 and 9.8 µM for USP2, USP7 and SENP2 respectively). NSC-632839 does not affect proteasome proteolytic activity. Induces apoptosis via a Bcl-2-dependent but apoptosome-independent mitochondrial pathway.
2570 | DUB Inhibitor, NSC-632839 DataSheet
Alternate Name/Synonyms: 3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride
Appearance: Yellow solid
Formulation: N/A
CAS Number: 157654-67-6
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₁H₂₁NO · HCl
Molecular Weight: 339.86
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~8 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A pan-specific ubiquitin isopeptidase inhibitor
MDL Number: N/A
PubChem CID: 5351362
SMILES: CC1=CC=C(C=C1)C=C2CNCC(=CC3=CC=C(C=C3)C)C2=O.Cl
InChi: InChI=1S/C21H21NO.ClH/c1-15-3-7-17(8-4-15)11-19-13-22-14-20(21(19)23)12-18-9-5-16(2)6-10-18;/h3-12,22H,13-14H2,1-2H3;1H/b19-11+,20-12+;
InChi Key: ZOKZLTXPTLIWOJ-BYCVLTJGSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |