Description
DuP-697 is a potent and selective inhibitor of cyclooxygenase-2 (IC₅₀ values are 10 and 800 nM for COX-2 and COX-1 respectively). Inhibits prostaglandin synthesis and is anti-inflammatory in vivo.
DuP-697 is a potent and selective inhibitor of cyclooxygenase-2 (IC₅₀ values are 10 and 800 nM for COX-2 and COX-1 respectively). Inhibits prostaglandin synthesis and is anti-inflammatory in vivo.
Alternate Name/Synonyms: 5-bromo-2-(4-fluorophenyl)-3-(4-(methylsulfonyl)phenyl)-thiophene
Appearance: White solid
Formulation: N/A
CAS Number: 88149-94-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₁₇H₁₂BrFO₂S₂
Molecular Weight: 411.3
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>30 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: a potent and selective cyclooxygenase-2 (COX-2) inhibitor
MDL Number: N/A
PubChem CID: 3177
SMILES: CS(=O)(=O)C1=CC=C(C=C1)C2=C(SC(=C2)Br)C3=CC=C(C=C3)F
InChi: InChI=1S/C17H12BrFO2S2/c1-23(20,21)14-8-4-11(5-9-14)15-10-16(18)22-17(15)12-2-6-13(19)7-3-12/h2-10H,1H3
InChi Key: AJFTZWGGHJXZOB-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |