Description
DUSP2 Polyclonal Antibody | E-AB-16397 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: Dual specificity phosphatase 2, Dual specificity protein phosphatase 2, Dual specificity protein phosphatase PAC 1, Dual specificity protein phosphatase PAC-1, DUS2, DUSP 2, DUSP2, PAC 1, PAC1, Serine/threonine specific protein phosphatase
Application: WB, IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell biology, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction
Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.
Concentration: 0.3 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human DUSP2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:200-1:1000, IHC 1:25-1:100
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 34 kDa
Molecular Weight(Observed): N/A