Dynamin 1 polyclonal Antibody | BS90432

Dynamin 1 polyclonal Antibody | BS90432 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB IHC

Application Range: WB:1:500-1:1,000 IHC:1:50-1:200

Background: Members of the Dynamin family, including Dynamin I and Dynamin II, are GTPase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression found in testis. Both dynamin proteins contain SH3 and proline-rich domains that mediate interactions between the dynamins and effectors of their GTPase activity) . The interactions with these effectors, which include microtubules, acidic phospholipids and SH3 domain-containing proteins, are required for rapid endocytosis. Dynamin I appears to be recruited to clathrin coated pits by SH3 domain interaction with amphiphysin, a protein highly expressed in brain.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: Dynamin 1 polyclonal Antibody detects endogenous levels of Dynamin 1 protein.

Molecular Weight: 97 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: DNM1, DNM, B dynamin, D100, DNM 1, DNM, DNM1, DYN1, Dynamin, Dynamin-1, Dynamin1,

Immunogen: Recombinant protein within human Dynamin 1 aa 575-750.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein affinity purified.

Pathway: