Dynamin 2 polyclonal Antibody | BS90433

Dynamin 2 polyclonal Antibody | BS90433 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB ICC/IF IHC FC

Application Range: WB:1:500-1:1,000 ICC:1:100-1:500 IHC:1:50-1:200 FC:1:50-1:100

Background: Members of the dynamin family, including Dynamin I and Dynamin II, are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression found in testis. Both dynamin proteins contain SH3 and proline-rich domains that mediate interactions between the dynamins and effectors of their GTPase activity. The interactions with these effectors, which include microtubules, acidic phospholipids and SH3 domain-containing proteins, are required for rapid endocytosis. Dynamin I appears to be recruited to clathrin coated pits by SH3 domain interaction with amphiphysin, a protein highly expressed in brain.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Dynamin 2 polyclonal Antibody detects endogenous levels of Dynamin 2 protein.

Molecular Weight: 98 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: DNM2, DYN2, CMT2M, CMTDI1, CMTDIB, DI CMTB, Dnm2, DYN II, DYN2, DYN2, Dynamin II, Dynamin-2, Dynamin2, DynaminII, DYNII,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: