EBV Early Antigens Antibody [1108-1] | 33-244

EBV Early Antigens Antibody [1108-1] | 33-244 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Epstein-Barr Virus

Homology: N/A

Immunogen: Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt���s lymphoma sera were used as the immunogen for this Early Antigens antibody.

Research Area: Other

Tested Application: IF

Application: IF: 0.5-1 ug/ml
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Early Antigens antibody to be titered up or down for optimal performance.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Protein G purified antibody

Clonality: Monoclonal

Clone: 1108-1

Isotype: IgG1, kappa

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Concentration: 0.2 mg/mL

Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.

Alternate Name: N/A

User Note: Optimal dilutions for each application to be determined by the researcher

BACKGROUND: Epstein-Barr virus (EBV) , also designated human herpesvirus 4 (HHV-4) , is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (EaD) and restricted (EaR) components. The activity of EaD is suppressed during latent infection. BMRF1, the gene that encodes for EaD, is closely associated with the gene encoding for EBV DNA polymerase, and EaD is essential for the activity of this polymerase. EaD forms a complex with EBV DNase and, together, they may play a role in viral replication.