ECSCR Antibody (C-term) [APR31612G]

ECSCR Antibody (C-term) [APR31612G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ECSCR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-165 amino acids from the C-terminal region of human ECSCR.

Cellular Localisation: Cell membrane; Single-pass type I membrane protein. Cytoplasm

Molecular Weight: 21295

Clone: Polyclonal

Gene Name: ECSCR

Gene ID: 641700

Function: Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2.

Summary: Tissue Location: Highest expression in endothelial cells. Also detected in vascular smooth muscle, macrophages, lymphocytes, and mast cells.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Endothelial cell-specific chemotaxis regulator, Apoptosis regulator through modulating IAP expression, ARIA, Endothelial cell-specific molecule 2, ECSCR, ECSM2