EFR3A Antibody (C-term) [APR05366G]

EFR3A Antibody (C-term) [APR05366G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This EFR3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 636-664 amino acids from the C-terminal region of human EFR3A.

Cellular Localisation: Cell membrane; Lipid-anchor. Cytoplasm, cytosol. Note=Palmitoylation anchors the protein to the plasma membrane (PubMed:23229899, PubMed:25380825, PubMed:26571211) . A small amount is observed in the cytosol (PubMed:25380825) .

Molecular Weight: 92924

Clone: Polyclonal

Gene Name: EFR3A (HGNC:28970)

Gene ID: 23167

Function: Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane (PubMed:23229899, PubMed:25608530, PubMed:26571211) . The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns (4) P) synthesis (Probable) . In the complex, EFR3A probably acts as the membrane-anchoring component (PubMed:23229899) . Also involved in responsiveness to G-protein-coupled receptors; it is however unclear whether this role is direct or indirect (PubMed:25380825) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC

Dilution: WB--1:1000 FC--1:10~50

Synonyms: Protein EFR3 homolog A, Protein EFR3-like, EFR3A, KIAA0143