EFTUD1 Antibody (C-term) [APR30594G]

EFTUD1 Antibody (C-term) [APR30594G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This EFTUD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1062-1090 amino acids from the C-terminal region of human EFTUD1.

Cellular Localisation: N/A

Molecular Weight: 125430

Clone: Polyclonal

Gene Name: EFL1 (HGNC:25789)

Gene ID: 79631

Function: Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.

Summary: Tissue Location: Expressed at low levels in brain. Expression is highly increased in glioma tissues.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, FC

Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Synonyms: Elongation factor Tu GTP-binding domain-containing protein 1, Elongation factor-like 1, Protein FAM42A, EFTUD1, EFL1, FAM42A