Description
EGLN2 Antibody | 18-590 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human EGLN2 (NP_444274.1) .
Research Area: Cancer
Tested Application: WB, IP
Application: WB: 1:500 - 1:2000
IP: 1:20 - 1:50
Specificiy: N/A
Positive Control 1: HeLa
Positive Control 2: A-549
Positive Control 3: HepG2
Positive Control 4: U-87MG
Positive Control 5: MCF-7
Positive Control 6: Mouse brain
Molecular Weight: Observed: 43kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: EGLN2, EIT6, PHD1, HPH-1, HPH-3, HIFPH1, HIF-PH1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene.