EGLN2 Antibody | 18-590

EGLN2 Antibody | 18-590 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human EGLN2 (NP_444274.1) .

Research Area: Cancer

Tested Application: WB, IP

Application: WB: 1:500 - 1:2000
IP: 1:20 - 1:50

Specificiy: N/A

Positive Control 1: HeLa

Positive Control 2: A-549

Positive Control 3: HepG2

Positive Control 4: U-87MG

Positive Control 5: MCF-7

Positive Control 6: Mouse brain

Molecular Weight: Observed: 43kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: EGLN2, EIT6, PHD1, HPH-1, HPH-3, HIFPH1, HIF-PH1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene.