Eif2ak2 Antibody | 15-086

Eif2ak2 Antibody | 15-086 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Rat

Homology: N/A

Immunogen: Recombinant protein of mouse Eif2ak2

Research Area: Apoptosis, Autophagy, Cell Cycle, Immunology, Signal Transduction

Tested Application: IHC

Application: IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: 2310047A08Rik, 4732414G15Rik, AI467567, AI747578, Pkr, Prkr, Tik, interferon-induced, double-stranded RNA-activated protein kinase, IFN- type I-induced and dsRNA-activated kinase, IFN-induced and double-stranded RNA-activated kinase, P1/eIF-2A protein kinase, T-cell viral integration site, dsRNA-activated kinase, eIF-2 alpha, eIF-2A protein kinase 2, interferon-inducible RNA-dependent protein kinase, p68 kinase, protein kinase R, protein kinase RNA-activated, protein kinase, interferon-inducible double stranded RNA dependent, serine/threonine-protein kinase TIK, tyrosine-protein kinase EIF2AK2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.