Elbasvir | 10-025

Elbasvir | 10-025 | Gentaur UK, US & Europe Distribution

BNR: Chemical

Predicted Molecular Weight: 882

Physical State: Lyophilized

Storage Condition: Short Term Storage:+4C. Long Term Storage: -20C. Handling Advice: Protect from light. Use/Stability: Stable for at least 2 years after receipt when stored at -20C.

Alternate Name: MK-8742

Background: Elbasvir is a direct-acting antiviral drug that potently inhibits hepatitis C virus (HCV) non-structural protein 5A (NS5A) . NS5A is essential for HCV RNA synthesis and viral assembly, and elbasvir inhibits the assembly of new viral replicase complexes when used at a concentration of 50 pM. It exhibits potent inhibitory activity against a broad range of HCV genotypes. Formulations containing elbasvir have been used alone and in combination with NS3/4A protease inhibitors in the treatment of HCV. Identified as a potential inhibitor of SARS-CoV-2, responsible for COVID-19.

Disclaimer: This product is for research use only.

Purity: greater than or equal to 98% (HPLC)

Formula: C49H55N9O7

Source: N/A

Solubility: Soluble in DMSO (30mg/ml) or DMF (30mg/ml) .

InChi Key: BVAZQCUMNICBAQ-ISSDNXAZSA-N

Smiles: O=C (N1CCCC1C2=NC=C (C3=CC4=C (N (C5=C4) [C@@H] (OC6=C5C=CC (C7=CN=C (N7) [C@@H]8CCCN8C ([C@H] (C (C) C) NC (OC) =O) =O) =C6) C9=CC=CC=C9) C=C3) N2) [C@@H] (NC (OC) =O) C (C) C

RTECS: N/A

Identity: Determined by 1H-NMR.

Merck Index: N/A