Description
Elcatonin is a Calcitonin derivative which is transformed from eel´s calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis. Elcatonin synthetic is a single, non-glycosylated polypeptide chain containing 31 amino acids.
Biomolecule/Target: Elcatonin
Synonyms: Elcatonin, 60731-46-6
Alternates names: Elcatonin, 60731-46-6
Taglines: A calcitonin derivative used as an anti-parathyroid agent
NCBI Gene ID #: 2246
NCBI Gene Symbol: FGF-1
Gene Source: N/A
Accession #: P05230
Recombinant: No
Source: Synthetic
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: 94%
Assay #2: HPLC
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: Biological Activity (based on net peptide) was found to be 6065 IU/mg
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: N/A
Concentration: N/A
Appearance: Lyophilized
Physical form description: Sterile filtered and lyophilized with no additives
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile dW to a concentration 100 µg/ml. This solution can then be diluted into other aqueous buffers and stored at 4 °C for 2-7 days and at -20 °C for future use.
Amino acid sequence: N/A