Elesclomol (STA-4783) | B1815

Elesclomol is a novel anticancer agent that displays oxidative stress induction, pro-apoptotic, and potential antineoplastic activities. The mechanism underlying the proapoptotic activity of elesclomol is through the induction of ROS (reactive oxygen species) and oxidative stress. Elesclomol rapidly induces ROS in cancer cells, generating a transcription profile characteristic of an oxidative stress response.

Elesclomol is a novel anticancer agent that displays oxidative stress induction, pro-apoptotic, and potential antineoplastic activities. The mechanism underlying the proapoptotic activity of elesclomol is through the induction of ROS (reactive oxygen species) and oxidative stress. Elesclomol rapidly induces ROS in cancer cells, generating a transcription profile characteristic of an oxidative stress response.

B1815 | Elesclomol (STA-4783) DataSheet

Alternate Name/Synonyms: N'1,N'3-dimethyl-N'1,N'3-di(phenylcarbonothioyl)malonohydrazide; STA4783

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 488832-69-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₁₉H₂₀N₄O₂S₂

Molecular Weight: 400.52

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO ( >20 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A novel anticancer agent that displays oxidative stress induction, pro-apoptotic, and potential antineoplastic activities

MDL Number: N/A

PubChem CID: 300471

SMILES: CN(C(=S)C1=CC=CC=C1)NC(=O)CC(=O)NN(C)C(=S)C2=CC=CC=C2

InChi: InChI=1S/C19H20N4O2S2/c1-22(18(26)14-9-5-3-6-10-14)20-16(24)13-17(25)21-23(2)19(27)15-11-7-4-8-12-15/h3-12H,13H2,1-2H3,(H,20,24)(H,21,25)

InChi Key: BKJIXTWSNXCKJH-UHFFFAOYSA-N