Ellagic Acid | B1154

Ellagic acid is a potent anti-oxidant that displays anti-cancer and anti-mutagenic properties. It inhibits CK2 (casein kinase 2) selectively with IC₅₀ values of 40 nM. It moderately inhibits Topoisomerases I and II, Lyn, PKA catalytic subunit Lyk, GSK-3 and FGR. It has also shown to act as an uncompetitive inhibitor of arginine methyltransferase CARM1 and also known to block H3R17 methylation.

Ellagic acid is a potent anti-oxidant that displays anti-cancer and anti-mutagenic properties. It inhibits CK2 (casein kinase 2) selectively with IC₅₀ values of 40 nM. It moderately inhibits Topoisomerases I and II, Lyn, PKA catalytic subunit Lyk, GSK-3 and FGR. It has also shown to act as an uncompetitive inhibitor of arginine methyltransferase CARM1 and also known to block H3R17 methylation.

B1154 | Ellagic Acid DataSheet

Alternate Name/Synonyms: 4,4′,5,5′,6,6′-Hexahydroxydiphenic acid 2,6,2′,6′-dilactone

Appearance: Light brown or green grey solid

Formulation: N/A

CAS Number: 476-66-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₄H₆O₈

Molecular Weight: 302.19

Cell-Permeable?: Yes

Purity: ≥95% by HPLC

Solubilities: DMSO (~0.14 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent anti-oxidant and CARM1 inhibitor

MDL Number: MFCD00149494

PubChem CID: 5281855

SMILES: C1=C2C3=C(C(=C1O)O)OC(=O)C4=CC(=C(C(=C43)OC2=O)O)O

InChi: 1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H

InChi Key: AFSDNFLWKVMVRB-UHFFFAOYSA-N