Empagliflozin | 2877

Empagliflozin is a potent and selective SGLT-2 (sodium glucose co-transporter-2) inhibitor (IC₅₀ of 3.1 nM); displays >300-fold selectivity over SGLT-1, 4, 5 and 6. Antidiabetic agent.

Empagliflozin is a potent and selective SGLT-2 (sodium glucose co-transporter-2) inhibitor (IC₅₀ of 3.1 nM); displays >300-fold selectivity over SGLT-1, 4, 5 and 6. Antidiabetic agent.

2877 | Empagliflozin DataSheet

Alternate Name/Synonyms: (2S,3R,4R,5S,6R)-2-[4-chloro-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol; BI-10773

Appearance: Off-white solid

Formulation: N/A

CAS Number: 864070-44-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₂₇ClO₇

Molecular Weight: 450.91

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>100 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and selective SGLT-2 (sodium glucose co-transporter-2) inhibitor

MDL Number: MFCD22566222

PubChem CID: 11949646

SMILES: C1COCC1OC2=CC=C(C=C2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)Cl

InChi: InChI=1S/C23H27ClO7/c24-18-6-3-14(23-22(28)21(27)20(26)19(11-25)31-23)10-15(18)9-13-1-4-16(5-2-13)30-17-7-8-29-12-17/h1-6,10,17,19-23,25-28H,7-9,11-12H2/t17-,19+,20+,21-,22+,23-/m0/s1

InChi Key: OBWASQILIWPZMG-QZMOQZSNSA-N