Emtricitabine | B2678

Emtricitabine is a cytidine analog that acts as an inhibitor of reverse transcriptase, preventing replication of HIV-1 (EC50 = 10-20 nM) and hepatitis B (EC50 = 10-40 nM). It is activated through multistep intracellular phosphorylation by various cellular kinases. Emtricitabine is an antiviral drug used for the treatment of HIV infection.

Emtricitabine is a cytidine analog that acts as an inhibitor of reverse transcriptase, preventing replication of HIV-1 (EC50 = 10-20 nM) and hepatitis B (EC50 = 10-40 nM). It is activated through multistep intracellular phosphorylation by various cellular kinases. Emtricitabine is an antiviral drug used for the treatment of HIV infection.

B2678 | Emtricitabine DataSheet

Alternate Name/Synonyms: FTC,4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone,BW 1592,BW 524W91

Appearance: Crystalline solid

Formulation:

CAS Number: 143491-57-0

Structure Available?: TRUE

Peptide sequence: N/A

Salt Form: FALSE

Molecular Formula: C₈H₁₀FN₃O₃S

Molecular Weight: 247.2

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: ~30 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A reverse transcriptase inhibitor

MDL Number:

PubChem CID: 60877

SMILES: O=C1N([C@H]2O[C@@H](CO)SC2)C=C(F)C(N)=N1

InChi: InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6+/m0/s1

InChi Key: XQSPYNMVSIKCOC-NTSWFWBYSA-N