ENO1 Antibody, KO Validated | 13-583

ENO1 Antibody, KO Validated | 13-583 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-434 of human ENO1 (NP_001419.1) .

Research Area: Cancer, Signal Transduction, Transcription

Tested Application: WB, IF, IP

Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:100
IP: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: PC-3

Positive Control 2: Ramos

Positive Control 3: NCI-H460

Positive Control 4: HeLa

Positive Control 5: THP-1

Positive Control 6: Mouse kidney

Molecular Weight: Observed: 47kDa

Validation: Antibody is Knockout validated.

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: ENO1, NNE, PPH, MPB1, ENO1L1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.