ENPP7 Polyclonal Antibody | E-AB-12390

ENPP7 Polyclonal Antibody | E-AB-12390 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ALK SMase, Alk-SMase, Alkaline sphingomyelin phosphodiesterase, E-NPP 7, Ectonucleotide pyrophosphatase/phosphodiesterase 7, Ectonucleotide pyrophosphatase/phosphodiesterase family member 7, ENPP7, ENPP7, Intestinal alkaline sphingomyelinase, NPP-7

Application: WB, IHC, ELISA

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Background: Ectonucleotide pyrophosphatase/phosphodiesterase family member 7(E-NPP 7) also known asalkaline sphingomyelin phosphodiesterase(Alk-SMase) orintestinal alkaline sphingomyelinaseis anenzymethat in humans is encoded by theENPP7gene. Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity. Inhibited in a dose dependent manner by ATP, imidazole, orthovanadate and zinc ion. Not inhibited by ADP, AMP and EDTA. Detected in the colon (at protein level). Expressed in the duodenum, jejunum and liver and at low levels in the ileum. Expression was very low in the esophagus, stomach and colon.

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human ENPP7

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 52 kDa

Molecular Weight(Observed): N/A