Description
ENPP7 Polyclonal Antibody | E-AB-12390 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: ALK SMase, Alk-SMase, Alkaline sphingomyelin phosphodiesterase, E-NPP 7, Ectonucleotide pyrophosphatase/phosphodiesterase 7, Ectonucleotide pyrophosphatase/phosphodiesterase family member 7, ENPP7, ENPP7, Intestinal alkaline sphingomyelinase, NPP-7
Application: WB, IHC, ELISA
Reactivity: Human, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling
Background: Ectonucleotide pyrophosphatase/phosphodiesterase family member 7(E-NPP 7) also known asalkaline sphingomyelin phosphodiesterase(Alk-SMase) orintestinal alkaline sphingomyelinaseis anenzymethat in humans is encoded by theENPP7gene. Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity. Inhibited in a dose dependent manner by ATP, imidazole, orthovanadate and zinc ion. Not inhibited by ADP, AMP and EDTA. Detected in the colon (at protein level). Expressed in the duodenum, jejunum and liver and at low levels in the ileum. Expression was very low in the esophagus, stomach and colon.
Concentration: 0.4 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human ENPP7
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 52 kDa
Molecular Weight(Observed): N/A