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Enterokinase, human recombinant | 7136
- SKU:
- 26-7136-GEN
- Availability:
- Usually shipped in 5 working days
Description
Proteases (also called Proteolytic Enzymes, Peptidases, or Proteinases) are enzymes that hydrolyze the amide bonds within proteins or peptides. Most proteases act in a specific manner, hydrolyzing bonds at or adjacent to specific residues or a specific sequence of residues contained within the substrate protein or peptide. Proteases play an important role in most diseases and biological processes including prenatal and postnatal development, reproduction, signal transduction, the immune response, various autoimmune and degenerative diseases, and cancer. They are also an important research tool, frequently used in the analysis and production of proteins. Enterokinase sequentially cleaves carboxyl side of D-D-D-D-K. Human Enterokinase is expressed as a linear 1019 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of Enterokinase, which consists of two polypeptide chains (heavy chain and light chain) held together by a single disulfide bond, resulting in formation of a biologically active heterodimer. The heavy chain consists of 784 amino acid residues, and the light consists of 235 amino acid residues.
7136 | Enterokinase human recombinant DataSheet
Biomolecule/Target: Enterokinase
Synonyms: Serine protease 7, transmembrane protease serine 15, Enteropeptidase
Alternates names: IL-TIF, TIFa, IL-10-related T-cell-derived-inducible factor, IL-22, ILTIF, IL-D110, zcyto18, MGC79382, MGC79384, TIFIL-23
Taglines: Hydrolyzes the amide bonds within proteins or peptides
NCBI Gene ID #: 50616
NCBI Gene Symbol: IL22
Gene Source: Human
Accession #: Q9GZX6
Recombinant: Yes
Source: CHO cells
Purity by SDS-PAGEs: 97%
Assay: SDS-PAGE
Purity: N/A
Assay #2: HPLC
Endotoxin Level: < 0.2 ng/g of protein (<2EU/g).
Activity (Specifications/test method): Sequentially cleaves carboxyl side of D-D-D-D-K.
Biological activity: Recombinant IL-22 activates STAT following receptor-ligand interaction.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 16.8 kDa
Concentration: N/A
Appearance: Lyophilized powder
Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Sodium Phosphate, pH 7.5 and 1 mM Calcium Chloride.
Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum. This solution can then be stored at 4°C for 1 week or -20° for future use.
Amino acid sequence: N/A